Useful for dealing with medical issues like high stress, chronic pain, trouble sleeping, and mood disorders like depression, Domino is an indica strain that is known for its potency. Since its total body relaxation effects can lead to intense sedation and sleep, it is best to leave this strain for night usage. Additionally, Domino often has high levels of THC and should be used primarily by veterans of the marijuana world. This strain may be a bit to intense for newbies. Other effects include body tingles, a sense of transcendent bliss, and a solid mood boost.